When a wild sorority moves in next door to Mac and Kelly Radner’s home, the young couple faces a new set of challenges. With a baby to care for, the Radners quickly find themselves overwhelmed by the loud parties and disruptive behavior of their new neighbors. Desperate to reclaim their peace and protect their family, they turn to their old adversaries from the nearby fraternity—the same group of rowdy college guys who once made their lives a living nightmare. Now, the Radners and the fraternity brothers must team up to take down the unruly sorority sisters and restore order to their quiet suburban life.